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Role of nitroso radicals as drug targets in circulatory shock

A vast amount of circumstantial evidence implicates oxygen-derived free radicals (especially, superoxide and hydroxyl radical) and high-energy oxidants [such as peroxynitrite (OONO(−))] as mediators of shock and ischaemia/reperfusion injury. Reactive oxygen species can initiate a wide range of toxic...

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Detalhes bibliográficos
Main Authors: Esposito, Emanuela, Cuzzocrea, Salvatore
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707962/
https://ncbi.nlm.nih.gov/pubmed/19630831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00255.x
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