Human blood dendritic cells from allergic subjects have impaired capacity to produce interferon-α via TLR9

BACKGROUND: High affinity IgE receptor (FcεRI) expression on blood dendritic cells reportedly correlates with serum IgE levels. Our studies demonstrate that plasmacytoid dendritic cells (pDCs) secrete pro-inflammatory cytokines (IL-6, TNF-α) following FcεRI stimulation – a mode of activation that si...

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Auteurs principaux: Tversky, Jody R., Le, Trong V., Bieneman, Anja P., Chichester, Kristin L., Hamilton, Robert G., Schroeder, John T.
Format: Artigo
Langue:Inglês
Publié: 2008
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707903/
https://ncbi.nlm.nih.gov/pubmed/18318750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2222.2008.02954.x
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