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Relaxation of Purifying Selection on Live Attenuated Vaccine Strains of the Family Paxamyxoviridae

In wild-type sequences of three paramyxoviruses (measles virus, mumps virus, and Newcastle disease virus), nucleotide diversity at both non-coding sites and at nonsynonymous sites in coding regions was significantly reduced in comparison to that at synonymous sites. Likewise, both the mean and varia...

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Detalhes bibliográficos
Autor principal: Hughes, Austin L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707849/
https://ncbi.nlm.nih.gov/pubmed/19195493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.01.036
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