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Electron Transfer Dissociation of Peptides Generated by Microwave D-Cleavage Digestion of Proteins

The non-enzymatic digestion of proteins by microwave D-cleavage is an effective technique for site-specific cleavage at aspartic acid (D). This specific cleavage C-terminal to D residues leads to inherently large peptides (15–25 amino acids) that are usually relatively highly charged (above +3) when...

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Autori principali: Hauser, Nicolas J., Basile, Franco, Han, Hongling, McLuckey, Scott A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707827/
https://ncbi.nlm.nih.gov/pubmed/18363321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr700671z
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