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An Operationally Simple and Efficient Synthesis of Orthogonally Protected L-threo-β-Hydroxyasparagine
A synthesis of orthogonally protected L-threo-β-hydroxyasparagine from L-aspartic acid is reported. Iodocyclization of 3-benzoylaminoaspartic acid provided an intermediate oxazoline dicarboxylate that was efficiently hydrolyzed to L-threo-β-hydroxyaspartic acid. The synthetic route for conversion of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707822/ https://ncbi.nlm.nih.gov/pubmed/19593390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-2007-982544 |
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