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The Occurrence of Aging-Dependent Reticulon 3 Immunoreactive Dystrophic Neurites Decreases Cognitive Function

Reticulon 3 (RTN3) has been shown to mark a distinct and abundant population of dystrophic neurites named RTN3 immunoreactive dystrophic neurites (RIDNs) in patients' brains of Alzheimer disease (AD). Transgenic mice expressing RTN3 (Tg-RTN3) also spontaneously develop RIDNs. To determine wheth...

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Detalhes bibliográficos
Main Authors: Shi, Qi, Hu, Xiangyou, Prior, Marguerite, Yan, Riqiang
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707820/
https://ncbi.nlm.nih.gov/pubmed/19386906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5887-08.2009
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