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HUMAN MITOCHONDRIAL C(1)-TETRAHYDROFOLATE SYNTHASE: SUBMITOCHONDRIAL LOCALIZATION OF THE FULL-LENGTH ENZYME AND CHARACTERIZATION OF A SHORT ISOFORM
Mammalian mitochondrial C(1)-tetrahydrofolate (THF) synthase (MTHFD1L gene product) is a monofunctional 10-formyl-THF synthetase, lacking the 5,10-methylene-THF dehydrogenase and 5,10-methenyl-THF cyclohydrolase activities typically found in the trifunctional cytoplasmic proteins. Here we report the...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2707772/ https://ncbi.nlm.nih.gov/pubmed/18996079 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.10.028 |
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