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Outcomes in Clinical Trials of Inhaled Corticosteroids for Children with Asthma Are Narrowly Focussed on Short Term Disease Activity

BACKGROUND: Little work has been done to determine which outcomes should be measured in randomised controlled trials (RCTs) in children with asthma. Drug regulatory authorities require that short term disease activity is measured, but other outcome domains are not mandatory for licensing and marketi...

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Главные авторы: Sinha, Ian P., Williamson, Paula R., Smyth, Rosalind L.
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707602/
https://ncbi.nlm.nih.gov/pubmed/19609438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006276
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