In vitro activity of the β-lactamase inhibitor NXL104 against KPC-2 carbapenemase and Enterobacteriaceae expressing KPC carbapenemases

BACKGROUND: NXL104 is a novel-structure β-lactamase inhibitor with potent activity against both class A and class C enzymes. Among the class A carbapenemases, KPC-type enzymes are now spreading rapidly and KPC-related carbapenemase resistance is an emerging phenomenon of great clinical importance. T...

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Main Authors: Stachyra, Thérèse, Levasseur, Premavathy, Péchereau, Marie-Claude, Girard, Anne-Marie, Claudon, Monique, Miossec, Christine, Black, Michael T.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707266/
https://ncbi.nlm.nih.gov/pubmed/19493866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkp197
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