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Role of TLR-4 in Liver Macrophage and Endothelial Cell Responsiveness During Acute Endotoxemia

Liver macrophages and endothelial cells have been implicated in hepatotoxicity induced by endotoxin (ETX). In these studies, we analyzed the role of toll-like receptor 4 (TLR-4) in the response of these cells to acute endotoxemia. Treatment of control C3H/OuJ mice with ETX (3 mg/kg, i.p.) resulted i...

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Detalhes bibliográficos
Main Authors: Chen, Li C., Gordon, Ronald E., Laskin, Jeffrey D., Laskin, Debra L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707258/
https://ncbi.nlm.nih.gov/pubmed/17996232
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2007.08.015
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