CAPS Activity in Priming Vesicle Exocytosis Requires CK2 Phosphorylation

CAPS (Ca(2+)-dependent activator protein for secretion) functions in priming Ca(2+)-dependent vesicle exocytosis, but the regulation of CAPS activity has not been characterized. Here we show that phosphorylation by protein kinase CK2 is required for CAPS activity. Dephosphorylation eliminated CAPS a...

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Hauptverfasser: Nojiri, Mari, Loyet, Kelly M., Klenchin, Vadim A., Kabachinski, Gregory, Martin, Thomas F. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2009
Schlagworte:
Molecular Basis of Cell and Developmental Biology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707249/
https://ncbi.nlm.nih.gov/pubmed/19460754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.017483
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