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Gene Conversion between the X Chromosome and the Male-Specific Region of the Y Chromosome at a Translocation Hotspot

Outside the pseudoautosomal regions, the mammalian sex chromosomes are thought to have been genetically isolated for up to 350 million years. However, in humans pathogenic XY translocations occur in XY-homologous (gametologous) regions, causing sex-reversal and infertility. Gene conversion might acc...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Rosser, Zoë H., Balaresque, Patricia, Jobling, Mark A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Elsevier 2009
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706966/
https://ncbi.nlm.nih.gov/pubmed/19576564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.06.009
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