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Gene Ontology Analysis of GWA Study Data Sets Provides Insights into the Biology of Bipolar Disorder
We present a method for testing overrepresentation of biological pathways, indexed by gene-ontology terms, in lists of significant SNPs from genome-wide association studies. This method corrects for linkage disequilibrium between SNPs, variable gene size, and multiple testing of nonindependent pathw...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706963/ https://ncbi.nlm.nih.gov/pubmed/19539887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2009.05.011 |
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