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PROTEASES INDUCE PRODUCTION OF THYMIC STROMAL LYMPHOPOIETIN BY AIRWAY EPITHELIAL CELLS THROUGH PROTEASE-ACTIVATED RECEPTOR-2

Thymic stromal lymphopoietin (TSLP) is produced by epithelial cells and triggers dendritic cell-mediated Th2-type inflammation. While TSLP is upregulated in epithelium of patients with asthma, the factors that control TSLP production have not been studied extensively. Because mouse models suggest ro...

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Detalhes bibliográficos
Main Authors: Kouzaki, Hideaki, O’Grady, Scott M., Lawrence, Christopher B., Kita, Hirohito
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706924/
https://ncbi.nlm.nih.gov/pubmed/19561109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0900904
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