Bench-to-bedside review: Severe lactic acidosis in HIV patients treated with nucleoside analogue reverse transcriptase inhibitors

Nucleoside reverse transcriptase inhibitors (NRTIs) are effective antiretroviral therapy for the treatment of HIV-infected patients. NRTIs can induce mitochondrial impairment that leads to a number of adverse events, including symptomatic lactic acidosis. In the present review, we describe the under...

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Pubblicato in:	Crit Care
Autori principali:	Claessens, Yann-Erick, Chiche, Jean-Daniel, Mira, Jean-Paul, Cariou, Alain
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2003
Soggetti:	Review
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC270672/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12793872/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/cc2162
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