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Experimental infection model for Sin Nombre hantavirus in the deer mouse (Peromyscus maniculatus)

The relationship between hantaviruses and their reservoir hosts is not well understood. We successfully passaged a mouse-adapted strain of Sin Nombre virus from deer mice (Peromyscus maniculatus) by i.m. inoculation of 4- to 6-wk-old deer mouse pups. After inoculation with 5 ID(50), antibodies to th...

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Detalhes bibliográficos
Main Authors: Botten, Jason, Mirowsky, Katy, Kusewitt, Donna, Bharadwaj, Mausumi, Yee, Joyce, Ricci, Roy, Feddersen, Richard M., Hjelle, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC27067/
https://ncbi.nlm.nih.gov/pubmed/10973478
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