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Monoclonal antibodies specific for Candida albicans Als3 that immunolabel fungal cells in vitro and in vivo and block adhesion to host surfaces

Two monoclonal antibodies (MAbs) were raised against the Candida albicans cell-surface glycoprotein Als3 using the N-terminal domain of the protein as the immunogen. ELISA was used to demonstrate the specificity of the MAbs for the Als3 fragment, but not for the corresponding N-terminal domain fragm...

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Detalhes bibliográficos
Main Authors: Coleman, David A., Oh, Soon-Hwan, Zhao, Xiaomin, Zhao, Hongyuan, Hutchins, Jeff T., Vernachio, John H., Patti, Joseph M., Hoyer, Lois L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706517/
https://ncbi.nlm.nih.gov/pubmed/19427882
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mimet.2009.05.002
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