Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)—dependent reprogramming of host macrophages to increase their interleukin-10 production

Sepsis causes over 200,000 deaths yearly in the US; better treatments are urgently needed. Administering bone marrow stromal cells (BMSCs—also known as mesenchymal stem cells) to mice before or shortly after inducing sepsis by cecal ligation and puncture reduced mortality and improved organ function...

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Detalhes bibliográficos
Main Authors: Németh, Krisztián, Leelahavanichkul, Asada, Yuen, Peter S T, Mayer, Balázs, Parmelee, Alissa, Doi, Kent, Robey, Pamela G, Leelahavanichkul, Kantima, Koller, Beverly H, Brown, Jared M, Hu, Xuzhen, Jelinek, Ivett, Star, Robert A, Mezey, Éva
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706487/
https://ncbi.nlm.nih.gov/pubmed/19098906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.1905
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