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Tumorigenic Stem and Progenitor Cells: Implications for the Therapeutic Index of Anti-cancer Agents
Cancer recurrence following response to therapy suggests that resistant cells lay dormant and subsequently reactivate. The cancer stem cell paradigm explains why tumors typically consist of a large therapy sensitive compartment, and a smaller compartment with profound intrinsic resistance. Here we e...
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| Auteurs principaux: | , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2007
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2706026/ https://ncbi.nlm.nih.gov/pubmed/17582641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.05.005 |
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