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Tumorigenic Stem and Progenitor Cells: Implications for the Therapeutic Index of Anti-cancer Agents

Cancer recurrence following response to therapy suggests that resistant cells lay dormant and subsequently reactivate. The cancer stem cell paradigm explains why tumors typically consist of a large therapy sensitive compartment, and a smaller compartment with profound intrinsic resistance. Here we e...

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Détails bibliographiques
Auteurs principaux: Donnenberg, Vera S., Landreneau, Rodney J., Donnenberg, Albert D.
Format: Artigo
Langue:Inglês
Publié: 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2706026/
https://ncbi.nlm.nih.gov/pubmed/17582641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2007.05.005
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