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Coupling of a Vented Column with Splitless NanoRPLC-ESI-MS for the Improved Separation and Detection of Brain Natriuretic Peptide-32 and its Proteolytic Peptides

The circulating concentration of a biomarker for congestive heart failure, Brain (B-type) Natriuretic Peptide (BNP-32), is measured using ELISA based assays in order to rapidly diagnose and monitor disease progression. The lack of molecular specificity afforded by these assays has recently come into...

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Detalhes bibliográficos
Main Authors: Andrews, Genna L., Shuford, Christopher M., Burnett, John C., Hawkridge, Adam M., Muddiman, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705968/
https://ncbi.nlm.nih.gov/pubmed/19269262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jchromb.2009.02.040
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