The origin and global emergence of adamantane resistant A/H3N2 influenza viruses

Resistance to the adamantane class of antiviral drugs by human A/H3N2 influenza viruses currently exceeds 90% in the United States and multiple Asian countries. Adamantane resistance is associated with a single amino acid change (S31N) in the M2 protein, which was shown to rapidly disseminate global...

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Main Authors: Nelson, Martha I., Simonsen, Lone, Viboud, Cécile, Miller, Mark A., Holmes, Edward C.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Inc. Published by Elsevier Inc. 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705899/
https://ncbi.nlm.nih.gov/pubmed/19394063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2009.03.026
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