New Target Genes for the Peroxisome Proliferator-Activated Receptor-γ (PPARγ) Antitumour Activity: Perspectives from the Insulin Receptor

The insulin receptor (IR) plays a crucial role in mediating the metabolic and proliferative functions triggered by the peptide hormone insulin. There is considerable evidence that abnormalities in both IR expression and function may account for malignant transformation and tumour progression in some...

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Autori principali: Foti, Daniela P., Paonessa, Francesco, Chiefari, Eusebio, Brunetti, Antonio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2009
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Review Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705764/
https://ncbi.nlm.nih.gov/pubmed/19587804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2009/571365
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