Patterns of GATA3 and IL13 gene polymorphisms associated with childhood rhinitis and atopy in a birth cohort

BACKGROUND: GATA3 activates transcription of the T(H)2 cytokines, including IL13, an important step in the allergic inflammatory pathway. OBJECTIVE: We sought to identify associations of single nucleotide polymorphisms of the genes GATA3 and IL13 and their interactions with rhinitis and allergic sen...

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Hlavní autoři: Huebner, Marianne, Kim, Dong-Yun, Ewart, Susan, Karmaus, Wilfried, Sadeghnejad, Alireza, Arshad, Syed H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705662/
https://ncbi.nlm.nih.gov/pubmed/18037162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2007.09.020
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