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Effect of ER-β gene disruption on estrogenic regulation of anxiety in female mice

It has been shown that long-term estrogen treatment in gonadectomized female mice increases anxiety levels. On the other hand, a recent study has reported that estrogen may down-regulate the levels of anxiety by acting through estrogen receptor (ER) β. In the present study, we investigated the role...

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Main Authors: Tomihara, Kazuya, Soga, Tomoko, Nomura, Masayoshi, Korach, Kenneth S., Gustafsson, Jan-Åke, Pfaff, Donald W., Ogawa, Sonoko
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705464/
https://ncbi.nlm.nih.gov/pubmed/18996135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2008.10.014
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