Left cardiac isomerism in the Sonic hedgehog null mouse

Sonic hedgehog (Shh) is a secreted morphogen necessary for the production of sidedness in the developing embryo. In this study, we describe the morphology of the atrial chambers and atrioventricular junctions of the Shh null mouse heart. We demonstrate that the essential phenotypic feature is isomer...

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Detalhes bibliográficos
Main Authors: Hildreth, Victoria, Webb, Sandra, Chaudhry, Bill, Peat, Jonathan D, Phillips, Helen M, Brown, Nigel, Anderson, Robert H, Henderson, Deborah J
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705298/
https://ncbi.nlm.nih.gov/pubmed/19538633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-7580.2009.01087.x
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