Asymmetric CLASP-dependent nucleation of non-centrosomal microtubules at the trans-Golgi network

Proper organization of microtubule arrays is essential for intracellular trafficking and cell motility. It is generally assumed that most if not all microtubules in vertebrate somatic cells are formed by the centrosome. Here we demonstrate that a large number of microtubules in untreated human cells...

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Auteurs principaux: Efimov, Andrey, Kharitonov, Alexey, Efimova, Nadia, Loncarek, Jadranka, Miller, Paul M., Andreyeva, Natalia, Gleeson, Paul, Galjart, Niels, Maia, Ana R. R., McLeod, Ian X., Yates, John R., Maiato, Helder, Khodjakov, Alexey, Akhmanova, Anna, Kaverina, Irina
Format: Artigo
Langue:Inglês
Publié: 2007
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705290/
https://ncbi.nlm.nih.gov/pubmed/17543864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2007.04.002
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