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Seeing the forest for the trees: using the Gene Ontology to restructure hierarchical clustering

Motivation: There is a growing interest in improving the cluster analysis of expression data by incorporating into it prior knowledge, such as the Gene Ontology (GO) annotations of genes, in order to improve the biological relevance of the clusters that are subjected to subsequent scrutiny. The stru...

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Détails bibliographiques
Auteurs principaux: Dotan-Cohen, Dikla, Kasif, Simon, Melkman, Avraham A.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2705235/
https://ncbi.nlm.nih.gov/pubmed/19497934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btp327
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