Common Genetic Variation Near the Phospholamban Gene Is Associated with Cardiac Repolarisation: Meta-Analysis of Three Genome-Wide Association Studies

To identify loci affecting the electrocardiographic QT interval, a measure of cardiac repolarisation associated with risk of ventricular arrhythmias and sudden cardiac death, we conducted a meta-analysis of three genome-wide association studies (GWAS) including 3,558 subjects from the TwinsUK and BR...

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Autori principali: Nolte, Ilja M., Wallace, Chris, Newhouse, Stephen J., Waggott, Daryl, Fu, Jingyuan, Soranzo, Nicole, Gwilliam, Rhian, Deloukas, Panos, Savelieva, Irina, Zheng, Dongling, Dalageorgou, Chrysoula, Farrall, Martin, Samani, Nilesh J., Connell, John, Brown, Morris, Dominiczak, Anna, Lathrop, Mark, Zeggini, Eleftheria, Wain, Louise V., Newton-Cheh, Christopher, Eijgelsheim, Mark, Rice, Kenneth, de Bakker, Paul I. W., Pfeufer, Arne, Sanna, Serena, Arking, Dan E., Asselbergs, Folkert W., Spector, Tim D., Carter, Nicholas D., Jeffery, Steve, Tobin, Martin, Caulfield, Mark, Snieder, Harold, Paterson, Andrew D., Munroe, Patricia B., Jamshidi, Yalda
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2009
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704957/
https://ncbi.nlm.nih.gov/pubmed/19587794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0006138
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