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Ryanodine receptor-mediated arrhythmias and sudden cardiac death
The cardiac ryanodine receptor-Ca(2+) release channel (RyR2) is an essential sarcoplasmic reticulum (SR) transmembrane protein that plays a central role in excitation–contraction coupling (ECC) in cardiomyocytes. Aberrant spontaneous, diastolic Ca(2+) leak from the SR due to dysfunctional RyR2 contr...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Pergamon Press
2009
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704947/ https://ncbi.nlm.nih.gov/pubmed/19345240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pharmthera.2009.03.006 |
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