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HIV-1 Tat C-terminus is cleaved by calpain 1: implication for Tat-mediated neurotoxicity
HIV-Encephalopathy (HIVE) is a common neurological disorder associated with HIV-1 infection and AIDS. The activity of the HIV trans-activating protein Tat is thought to contribute to neuronal pathogenesis. While Tat proteins from primary virus isolates consist of 101 or more amino acids, 72 and 86 a...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704945/ https://ncbi.nlm.nih.gov/pubmed/19022302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.10.010 |
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