Molecular analysis of a UDP-GlcNAc:polypeptide α-N-acetylglucosaminyltransferase implicated in the initiation of mucin-type O-glycosylation in Trypanosoma cruzi

Trypanosoma cruzi, the causative agent of Chagas disease, is surrounded by a mucin coat that plays important functions in parasite survival/invasion and is extensively O-glycosylated by Golgi and cell surface glycosyltransferases. The addition of the first sugar, α-N-acetylglucosamine (GlcNAc) linke...

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Main Authors: Heise, Norton, Singh, Divyendu, van der Wel, Hanke, Sassi, Slim O, Johnson, Jennifer M, Feasley, Christa L, Koeller, Carolina M, Previato, Jose O, Mendonça-Previato, Lucia, West, Christopher M
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
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Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704902/
https://ncbi.nlm.nih.gov/pubmed/19468051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/glycob/cwp068
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