Rescue of atypical protein kinase C in epithelia by the cytoskeleton and Hsp70 family chaperones

Atypical PKC (PKCι) is a key organizer of cellular asymmetry. Sequential extractions of intestinal cells showed a pool of enzymatically active PKCι and the chaperone Hsp70.1 attached to the apical cytoskeleton. Pull-down experiments using purified and recombinant proteins showed a complex of Hsp70 a...

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Main Authors: Mashukova, Anastasia, Oriolo, Andrea S., Wald, Flavia A., Casanova, M. Llanos, Kröger, Cornelia, Magin, Thomas M., Omary, M. Bishr, Salas, Pedro J. I.
格式: Artigo
語言:Inglês
出版: Company of Biologists 2009
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Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704884/
https://ncbi.nlm.nih.gov/pubmed/19549684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.046979
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