Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

We recently showed that the mammalian genome encodes >1,000 large intergenic noncoding (linc)RNAs that are clearly conserved across mammals and, thus, functional. Gene expression patterns have implicated these lincRNAs in diverse biological processes, including cell-cycle regulation, immune surve...

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Bibliografiske detaljer
Main Authors: Khalil, Ahmad M., Guttman, Mitchell, Huarte, Maite, Garber, Manuel, Raj, Arjun, Rivea Morales, Dianali, Thomas, Kelly, Presser, Aviva, Bernstein, Bradley E., van Oudenaarden, Alexander, Regev, Aviv, Lander, Eric S., Rinn, John L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2009
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704857/
https://ncbi.nlm.nih.gov/pubmed/19571010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0904715106
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