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Rhinovirus 3C Protease Can Localize in the Nucleus and Alter Active and Passive Nucleocytoplasmic Transport

The degradation of nuclear pore components and disruption of nucleocytoplasmic trafficking during rhinovirus infection have been attributed to viral 2A protease. Here we show for the first time that rhinovirus 3C protease may also have a role. Specifically, we show that 3C and its precursor, 3CD, ca...

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Detalhes bibliográficos
Main Authors: Ghildyal, Reena, Jordan, Benjamin, Li, Dongsheng, Dagher, Hayat, Bardin, Phillip G., Gern, James E., Jans, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704779/
https://ncbi.nlm.nih.gov/pubmed/19403669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01748-08
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