Simulation and Prediction of the Adaptive Immune Response to Influenza A Virus Infection

The cellular immune response to primary influenza virus infection is complex, involving multiple cell types and anatomical compartments, and is difficult to measure directly. Here we develop a two-compartment model that quantifies the interplay between viral replication and adaptive immunity. The fi...

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Bibliographic Details
Main Authors: Lee, Ha Youn, Topham, David J., Park, Sung Yong, Hollenbaugh, Joseph, Treanor, John, Mosmann, Tim R., Jin, Xia, Ward, Brian M., Miao, Hongyu, Holden-Wiltse, Jeanne, Perelson, Alan S., Zand, Martin, Wu, Hulin
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2009
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704765/
https://ncbi.nlm.nih.gov/pubmed/19439465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00098-09
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