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Adenovirus Vectors Expressing Hantavirus Proteins Protect Hamsters against Lethal Challenge with Andes Virus

Hantaviruses infect humans following aerosolization from rodent feces and urine, producing hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Due to the high rates of mortality and lack of therapies, vaccines are urgently needed. Nonreplicating adenovirus (Ad) vectors that expr...

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Bibliografiske detaljer
Main Authors: Safronetz, David, Hegde, Nagendra R., Ebihara, Hideki, Denton, Michael, Kobinger, Gary P., St. Jeor, Stephen, Feldmann, Heinz, Johnson, David C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704762/
https://ncbi.nlm.nih.gov/pubmed/19403663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00373-09
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