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Substrate-Induced Inactivation of the Escherichia coli AmiD N-Acetylmuramoyl-l-Alanine Amidase Highlights a New Strategy To Inhibit This Class of Enzyme
In the eubacterial cell, the peptidoglycan is perpetually hydrolyzed throughout the cell cycle by different enzymes such as lytic transglycosylases, endopeptidases, and amidases. In Escherichia coli, four N-acetylmuramoyl-l-alanine amidases, AmiA, -B, -C, and -D, are present in the periplasm. AmiA,...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
2009
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704666/ https://ncbi.nlm.nih.gov/pubmed/19237650 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01520-07 |
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