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Renal Disposition of Colistin in the Isolated Perfused Rat Kidney

Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption of colistin by the kidney in vivo, but there is no knowledge of its disposition within the kidney. This study in...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Ma, Zheng, Wang, Jiping, Nation, Roger L., Li, Jian, Turnidge, John D., Coulthard, Kingsley, Milne, Robert W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704651/
https://ncbi.nlm.nih.gov/pubmed/19380593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00030-09
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