Renal Disposition of Colistin in the Isolated Perfused Rat Kidney

Nephrotoxicity is an important limitation to the clinical use of colistin against Pseudomonas aeruginosa and other gram-negative pathogens. Previous work reported net tubular reabsorption of colistin by the kidney in vivo, but there is no knowledge of its disposition within the kidney. This study in...

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Bibliografiske detaljer
Main Authors: Ma, Zheng, Wang, Jiping, Nation, Roger L., Li, Jian, Turnidge, John D., Coulthard, Kingsley, Milne, Robert W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Pharmacology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704651/
https://ncbi.nlm.nih.gov/pubmed/19380593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00030-09
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