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Increased IκBα expression is essential for the tolerogenic property of TGF-β-exposed APCs
IκBα is an inhibitor of the transcriptional factor NF-κB, and it is an essential component of the signaling pathways that lead to expression of inflammatory molecules. These include cytokines and costimulatory molecules associated with antigen presentation in an inflammatory immune response. In this...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Federation of American Societies for Experimental Biology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704595/ https://ncbi.nlm.nih.gov/pubmed/19237504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-124545 |
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