New class of microRNA targets containing simultaneous 5′-UTR and 3′-UTR interaction sites

MicroRNAs (miRNAs) are known to post-transcriptionally regulate target mRNAs through the 3′-UTR, which interacts mainly with the 5′-end of miRNA in animals. Here we identify many endogenous motifs within human 5′-UTRs specific to the 3′-ends of miRNAs. The 3′-end of conserved miRNAs in particular ha...

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Main Authors: Lee, Inhan, Ajay, Subramanian S., Yook, Jong In, Kim, Hyun Sil, Hong, Su Hyung, Kim, Nam Hee, Dhanasekaran, Saravana M., Chinnaiyan, Arul M., Athey, Brian D.
פורמט: Artigo
שפה:Inglês
יצא לאור: Cold Spring Harbor Laboratory Press 2009
נושאים:
Letter
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704433/
https://ncbi.nlm.nih.gov/pubmed/19336450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.089367.108
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