Lansoprazole, a Proton Pump Inhibitor, Suppresses Production of Tumor Necrosis Factor-α and Interleukin-1β Induced by Lipopolysaccharide and Helicobacter Pylori Bacterial Components in Human Monocytic Cells via Inhibition of Activation of Nuclear Factor-κB and Extracellular Signal-Regulated Kinase

Pathogenic bacterial components play critical roles in initiation of gastrointestinal inflammation via activation of intracellular signaling pathways which induce proinflammatory cytokines such as tumor necrosis factor (TNF)-α and interleukin (IL)-1β. Lansoprazole (LANSO), a proton pump inhibitor, h...

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Detalhes bibliográficos
Main Authors: Tanigawa, Tetsuya, Watanabe, Toshio, Higuchi, Kazuhide, Machida, Hirohisa, Okazaki, Hirotoshi, Yamagami, Hirokazu, Watanabe, Kenji, Tominaga, Kazunari, Fujiwara, Yasuhiro, Oshitani, Nobuhide, Arakawa, Tetsuo
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2009
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704330/
https://ncbi.nlm.nih.gov/pubmed/19590712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.08-267
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