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Uncoupling Protein 2 Ala55Val polymorphism is associated with a higher acute insulin response to glucose
Recent evidence suggests that mitochondrial uncoupling protein 2 (UCP2) in pancreatic β cells plays a crucial role in insulin production and secretion. We hypothesized that two UCP2 polymorphisms, a −55C/T (Ala55Val) substitution in exon 4 and an exon 8 insertion, would alter the acute insulin respo...
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Main Authors: | , , , , , , |
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格式: | Artigo |
語言: | Inglês |
出版: |
2009
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2704067/ https://ncbi.nlm.nih.gov/pubmed/19368944 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.metabol.2009.02.016 |
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