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Long and short isoforms of Neurospora clock protein FRQ support temperature compensated circadian rhythms

The large (l) and small (s) isoforms of FREQUENCY (FRQ) are elements of interconnected feedback loops of the Neurospora circadian clock. The expression ratio of l-FRQ versus s-FRQ is regulated by thermosensitive splicing of an intron containing the initiation codon for l-FRQ. We show that this splic...

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Bibliographic Details
Main Authors: Diernfellner, Axel, Colot, Hildur V., Dintsis, Orfeas, Loros, Jennifer J., Dunlap, Jay C., Brunner, Michael
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704016/
https://ncbi.nlm.nih.gov/pubmed/18037381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.11.043
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