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IC(50)-to-K(i): a web-based tool for converting IC(50) to K(i) values for inhibitors of enzyme activity and ligand binding

A new web-server tool estimates K(i) values from experimentally determined IC(50) values for inhibitors of enzymes and of binding reactions between macromolecules (e.g. proteins, polynucleic acids) and ligands. This converter was developed to enable end users to help gauge the quality of the underly...

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Detalhes bibliográficos
Main Authors: Cer, R. Z., Mudunuri, U., Stephens, R., Lebeda, F. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703898/
https://ncbi.nlm.nih.gov/pubmed/19395593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp253
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