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IC(50)-to-K(i): a web-based tool for converting IC(50) to K(i) values for inhibitors of enzyme activity and ligand binding

A new web-server tool estimates K(i) values from experimentally determined IC(50) values for inhibitors of enzymes and of binding reactions between macromolecules (e.g. proteins, polynucleic acids) and ligands. This converter was developed to enable end users to help gauge the quality of the underly...

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Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Cer, R. Z., Mudunuri, U., Stephens, R., Lebeda, F. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703898/
https://ncbi.nlm.nih.gov/pubmed/19395593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp253
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