Interference with Hemozoin Formation Represents an Important Mechanism of Schistosomicidal Action of Antimalarial Quinoline Methanols

BACKGROUND: The parasitic trematode Schistosoma mansoni is one of the major causative agents of human schistosomiasis, which afflicts 200 million people worldwide. Praziquantel remains the main drug used for schistosomiasis treatment, and reliance on the single therapy has been prompting the search...

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Detalhes bibliográficos
Main Authors: Corrêa Soares, Juliana B. R., Menezes, Diego, Vannier-Santos, Marcos A., Ferreira-Pereira, Antonio, Almeida, Giulliana T., Venancio, Thiago M., Verjovski-Almeida, Sergio, Zishiri, Vincent K., Kuter, David, Hunter, Roger, Egan, Timothy J., Oliveira, Marcus F.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703804/
https://ncbi.nlm.nih.gov/pubmed/19597543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000477
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