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To Cross or Not to Cross: Alternatively Spliced Forms of the Robo3 Receptor Regulate Discrete Steps in Axonal Midline Crossing

How growth cones grow toward and then away from intermediate targets is a key issue in axon guidance. In this issue of Neuron, Tessier-Lavigne and colleagues demonstrate that two different spliced isoforms of the Robo3 receptor act sequentially in commissural neuron growth cones to mediate this proc...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Black, Douglas L., Zipursky, S. Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703741/
https://ncbi.nlm.nih.gov/pubmed/18466738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2008.04.019
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