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The anticancer activity of lytic peptides is inhibited by heparan sulfate on the surface of the tumor cells

BACKGROUND: Cationic antimicrobial peptides (CAPs) with antitumor activity constitute a promising group of novel anticancer agents. These peptides induce lysis of cancer cells through interactions with the plasma membrane. It is not known which cancer cell membrane components influence their suscept...

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Detalhes bibliográficos
Main Authors: Fadnes, Bodil, Rekdal, Øystein, Uhlin-Hansen, Lars
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703650/
https://ncbi.nlm.nih.gov/pubmed/19527490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-183
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