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GnRH Stimulates Expression of PACAP in the Pituitary Gonadotropes via Both the PKA and PKC Signaling Systems

Recent studies have demonstrated a clear role for pituitary adenylate cyclase-activating polypeptide (PACAP) in the regulation of gonadotropin biosynthesis and secretion, both alone and in conjunction with GnRH. First defined as a hypothalamic releasing factor, PACAP subsequently has been identified...

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Autori principali: Grafer, Constance M., Thomas, Robin, Lambrakos, Litsa, Montoya, Ignacio, White, Sheryl, Halvorson, Lisa M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703603/
https://ncbi.nlm.nih.gov/pubmed/19342443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2008-0477
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