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Anterograde flow of cargo across the Golgi stack potentially mediated via bidirectional “percolating” COPI vesicles

How do secretory proteins and other cargo targeted to post-Golgi locations traverse the Golgi stack? We report immunoelectron microscopy experiments establishing that a Golgi-restricted SNARE, GOS 28, is present in the same population of COPI vesicles as anterograde cargo marked by vesicular stomati...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Orci, Lelio, Ravazzola, Mariella, Volchuk, Allen, Engel, Thomas, Gmachl, Michael, Amherdt, Mylène, Perrelet, Alain, Söllner, Thomas H., Rothman, James E.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC27036/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10962035/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.190292497
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