Regulation of Aldosterone and Cortisol Production by the Transcriptional Repressor Neuron Restrictive Silencer Factor

Aldosterone synthase (CYP11B2) and 11β-hydroxylase (CYP11B1) regulate aldosterone and cortisol production, respectively. The expression of these enzymes is promoted by calcium influx through Cav3.2, a T-type calcium channel. Neuron-restrictive silencer factor (NRSF) binds to neuron-restrictive silen...

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Autors principals: Somekawa, Satoshi, Imagawa, Keiichi, Naya, Noriyuki, Takemoto, Yasuhiro, Onoue, Kenji, Okayama, Satoshi, Takeda, Yukiji, Kawata, Hiroyuki, Horii, Manabu, Nakajima, Tamio, Uemura, Shiro, Mochizuki, Naoki, Saito, Yoshihiko
Format: Artigo
Idioma:Inglês
Publicat: The Endocrine Society 2009
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2703558/
https://ncbi.nlm.nih.gov/pubmed/19342457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-1624
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